[CAS NO. 1869126-64-6] Azido-PEG4-Val-Cit-PAB-MMAE
PRODUCTS SPECIFICATIONS [1869126-64-6]
DESCRIPTION [1869126-64-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 1396.71 |
| Molecular Formula | C69H113N13O17 |
| SMILES | O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCN=[N+]=[N-])=O)=O)=O)=O)=O)=O)=O)OC)=O |
Summary
Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker Azido-PEG4-Val-Cit-PAB-OH [1] .
IC50 & Target
Drug-Linker Conjugates for ADC [1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, protect from light, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.