[CAS NO. 2229974-73-4] XY028-133
PRODUCTS SPECIFICATIONS [2229974-73-4]
DESCRIPTION [2229974-73-4]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 1002.23 |
| Molecular Formula | C53H67N11O7S |
| SMILES | O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCC(N4CCN(C5=CC=C(NC6=NC=C(C(C)=C(C(C)=O)C(N7C8CCCC8)=O)C7=N6)N=C5)CC4)=O)=O)=O)C[C@H](O)C3 |
Summary
IC50 & Target
|
CDK4 |
CDK6 |
In Vitro
XY028-133 (1 and 3 μM, 24 h) significantly decreases CDK4/6, Cyclin A, PLK1 and pRb protein levels in A375 cells [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 50 mg/mL ( 49.89 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 0.9978 mL | 4.9889 mL | 9.9778 mL |
| 5 mM | 0.1996 mL | 0.9978 mL | 1.9955 mL |
| 10 mM | 0.0998 mL | 0.4989 mL | 0.9978 mL |