[CAS NO. 2250323-50-1] JWG-071
PRODUCTS SPECIFICATIONS [2250323-50-1]
DESCRIPTION [2250323-50-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 612.76 |
| Molecular Formula | C34H44N8O3 |
| SMILES | COC1=CC(C(N2CCC(N3CCN(C)CC3)CC2)=O)=CC=C1NC4=NC=C(N(C)C5=O)C(N(C6=CC=CC=C65)C(C)CC)=N4 |
Summary
IC50 & Target
|
ERK5 88 nM (IC 50 ) |
In Vitro
JWG-071 inhibits ERK5 and LRRK2 with IC 50 of 88 and 109 nM, respectively [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 163.20 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.6320 mL | 8.1598 mL | 16.3196 mL |
| 5 mM | 0.3264 mL | 1.6320 mL | 3.2639 mL |
| 10 mM | 0.1632 mL | 0.8160 mL | 1.6320 mL |