[CAS NO. 2301916-69-6] PROTACFAKdegrader1
PRODUCTS SPECIFICATIONS [2301916-69-6]
DESCRIPTION [2301916-69-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 996.13 |
| Molecular Formula | C47H56F3N9O8S2 |
| SMILES | O=C(N[C@H](C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)C(C)(C)C)CCOCCOC4=CC=C(NC5=NC(NCC6=CC=CC(N(C)S(C)(=O)=O)=C6)=C(C(F)(F)F)C=N5)C=C4 |
3 Publications Citing Use of MCE
Summary
IC50 & Target
IC50: 6.5 nM (Focal adhesion kinase)
DC50: 3 nM (Focal adhesion kinase)
[1]
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 200 mg/mL ( 200.78 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.0039 mL | 5.0194 mL | 10.0389 mL |
| 5 mM | 0.2008 mL | 1.0039 mL | 2.0078 mL |
| 10 mM | 0.1004 mL | 0.5019 mL | 1.0039 mL |
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1.
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Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 5 mg/mL (5.02 mM); Clear solution