[CAS NO. 2411681-89-3]  Thalidomide-O-amido-PEG4-azide

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PRODUCTS SPECIFICATIONS [2411681-89-3]

Catalog
AS980159
Brand
Arctom Scientific
CAS
2411681-89-3

DESCRIPTION [2411681-89-3]

Overview

MDL-
Molecular Weight576.56
Molecular FormulaC25H32N6O10
SMILESO=C(NCCOCCOCCOCCOCCN=[N+]=[N-])COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

For research use only. We do not sell to patients.

Summary

Thalidomide-O-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1] .


IC50 & Target

PEGs


In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month