[CAS NO. 265989-46-6] 2-Hydroxyatorvastatincalciumsalt
PRODUCTS SPECIFICATIONS [265989-46-6]
DESCRIPTION [265989-46-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 594.69 |
| Molecular Formula | C33H35FN2O6.1/2Ca |
| SMILES | FC1=CC=C(C2=C(C3=CC=CC=C3)C(C(NC4=CC=CC=C4O)=O)=C(C(C)C)N2CC[C@@H](O)C[C@@H](O)CC(O)=O)C=C1.[Ca].[1/2] |
Summary
2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC 50 value of 8 nM.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 12.5 mg/mL ( 21.02 mM ; ultrasonic and adjust pH to 3 with HCl)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.6815 mL | 8.4077 mL | 16.8155 mL |
| 5 mM | 0.3363 mL | 1.6815 mL | 3.3631 mL |
| 10 mM | 0.1682 mL | 0.8408 mL | 1.6815 mL |
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Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 1.25 mg/mL (2.10 mM); Clear solution