[CAS NO. 30358-88-4] 3'-O-Acetylhamaudol

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PRODUCTS SPECIFICATIONS [30358-88-4]

Catalog

AS983348

Brand

Arctom Scientific

CAS

30358-88-4

DESCRIPTION [30358-88-4]

Overview

MDL	-
Molecular Weight	318.32
Molecular Formula	C17H18O6
SMILES	OC1=C(C[C@H](OC(C)=O)C(C)(C)O2)C2=CC(OC(C)=C3)=C1C3=O

For research use only. We do not sell to patients.

Summary

3'-O-Acetylhamaudol, isolated from Angelica polymorpha , exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation ^[1] .

Appearance

Solid

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 20 mg/mL ( 62.83 mM ; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.1415 mL	15.7075 mL	31.4149 mL
5 mM	0.6283 mL	3.1415 mL	6.2830 mL
10 mM	0.3141 mL	1.5707 mL	3.1415 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2 mg/mL (6.28 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2 mg/mL (6.28 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2 mg/mL (6.28 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Kimura Y, et al. Anti-tumor actions of major component 3'-O-acetylhamaudol of Angelica japonica roots through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation. Cancer Lett. 2008 Jun 28;265(1):84-97.

[CAS NO. 30358-88-4] 3'-​O-​Acetylhamaudol