[CAS NO. 888213-72-7] CPT-157633
PRODUCTS SPECIFICATIONS [888213-72-7]
DESCRIPTION [888213-72-7]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 465.20 |
| Molecular Formula | C12H16BrF2N2O6PS |
| SMILES | FC(C1=CC=C(C[C@H](NS(=O)(C)=O)C(NC)=O)C=C1Br)(P(O)(O)=O)F |
Summary
CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance [1] .
In Vivo
CPT-157633 (0.2 µg/day; intracerebroventricular infusion) alleviates the hypothalamic inflammation and glucose intolerance induced by binge drinking in rats [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 200 mg/mL ( 429.92 mM ; Need ultrasonic)
H 2 O : 100 mg/mL ( 214.96 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.1496 mL | 10.7481 mL | 21.4961 mL |
| 5 mM | 0.4299 mL | 2.1496 mL | 4.2992 mL |
| 10 mM | 0.2150 mL | 1.0748 mL | 2.1496 mL |
