| MDL | - |
|---|---|
| Molecular Weight | 192.26 |
| Molecular Formula | C8H20N2O3 |
| SMILES | NCCOCCOCCOCCN |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Liquid
Room temperature in continental US; may vary elsewhere.
| Pure form | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
H 2 O : 100 mg/mL ( 520.13 mM ; Need ultrasonic)
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 5.2013 mL | 26.0065 mL | 52.0129 mL |
| 5 mM | 1.0403 mL | 5.2013 mL | 10.4026 mL |
| 10 mM | 0.5201 mL | 2.6006 mL | 5.2013 mL |
Add each solvent one by one: PBS
Solubility: 100 mg/mL (520.13 mM); Clear solution; Need ultrasonic