[CAS NO. 929-75-9]  Amino-PEG3-C2-Amine

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PRODUCTS SPECIFICATIONS [929-75-9]

Distributor
Catalog
AS993982
Brand
Arctom Scientific
CAS
929-75-9

DESCRIPTION [929-75-9]

Overview

MDL-
Molecular Weight192.26
Molecular FormulaC8H20N2O3
SMILESNCCOCCOCCOCCN

For research use only. We do not sell to patients.

Summary

Amino-PEG3-C2-Amine is a PEG-based (3 units) PROTAC linker can be used in the synthesis of PROTACs .


In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Liquid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

H 2 O : 100 mg/mL ( 520.13 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2013 mL 26.0065 mL 52.0129 mL
5 mM 1.0403 mL 5.2013 mL 10.4026 mL
10 mM 0.5201 mL 2.6006 mL 5.2013 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 100 mg/mL (520.13 mM); Clear solution; Need ultrasonic

* All of the co-solvents are available by MCE.


Synonyms

Ethanamine, 2,2′-[oxybis(2,1-ethanediyloxy)]bis-
Ethylamine, 2,2′-[oxybis(ethyleneoxy)]bis-
2,2′-[Oxybis(2,1-ethanediyloxy)]bis[ethanamine]
Tetraethylene glycol diamine
1,11-Diamino-3,6,9-trioxaundecane
3,6,9-Trioxaundecane-1,11-diamine
Jeffamine EDR 192
Bis[2-(2-aminoethoxy)ethyl] ether
EDR 192
1,11-Diamine-3,6,9-trioxaundecane
2,2′-[[Oxybis(ethane-2,1-diyl)]bis(oxy)]diethanamine
2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethanamine
2,2′-[Oxybis(2,1-ethanediyloxy)]diethanamine
2-[2-[2-[2-Aminoethoxy]ethoxy]ethoxy]ethylamine