[CAS NO. 83-85-2] Fuscin

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PRODUCTS SPECIFICATIONS [83-85-2]

Catalog

HY-111321

Brand

MCE

CAS

83-85-2

DESCRIPTION [83-85-2]

Overview

MDL	-
Molecular Weight	276.28
Molecular Formula	C15H16O5
SMILES	O=C1C=C2C(C(C)O1)=C(O)C(C3=C2CCC(C)(C)O3)=O

For research use only. We do not sell to patients.

Summary

Fuscin, a fungal metabolite, CCR5 receptor antagonist with anti-HIV effects. Fuscin is a respiration and oxidative phosphorylation inhibitor, and also a mitochondrial SH-dependent transport-linked functions inhibitor ^[1] ^[2] ^[3] .

IC50 & Target

HIV

CCR5

Microbial Metabolite

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] K Yoganathan, et al. 10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum. J Nat Prod. 2003 Aug;66(8):1116-7.
[2] K S Cheah. Fuscin, an inhibitor of respiration and oxidative phosphorylation in ox-neck muscle mitochondria. Biochim Biophys Acta.1972 Jul 12;275(1):1-9.
[3] P M Vignais, et al. Fuscin, an inhibitor of mitochondrial SH-dependent transport-linked functions. Biochim Biophys Acta. 1973 Dec 14;325(3):357-74.