[CAS NO. ] N1-Methylpseudouridine-5′-triphosphate tetralithium

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PRODUCTS SPECIFICATIONS

Catalog

HY-112582B

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	521.90
Molecular Formula	C10H13Li4N2O15P3
SMILES	O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O

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Summary

N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) tetralithium is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability ^[1] .

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Andries O, Mc Cafferty S, De Smedt SC, Weiss R, Sanders NN, Kitada T. N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J Control Release. 2015;217:337-344.