[CAS NO. 869304-55-2] Eg5 Inhibitor V, trans-24

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PRODUCTS SPECIFICATIONS [869304-55-2]

Catalog

HY-112915

Brand

MCE

CAS

869304-55-2

DESCRIPTION [869304-55-2]

Overview

MDL	-
Molecular Weight	423.46
Molecular Formula	C26H21N3O3
SMILES	O=C([C@]1([H])CC2=C([C@@H](C3=CC=CC(O)=C3)N14)NC5=C2C=CC=C5)N(CC6=CC=CC=C6)C4=O

For research use only. We do not sell to patients.

Summary

Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC ₅₀ of 0.65 μM, and can be used in the research of cancer .

IC50 & Target

Eg5

0.65 μM (IC ₅₀ )

In Vitro

Eg5 Inhibitor V, trans-24 is a potent and specific Eg5 inhibitor with an IC ₅₀ of 0.65 μM, and can be used in the research of cancer ^[1] .

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

References

[1] Sunder-Plassmann N, et al. Synthesis and biological evaluation of new tetrahydro-beta-carbolines as inhibitors of the mitotic kinesin Eg5. Bioorg Med Chem. 2005 Nov 15;13(22):6094-111.