[CAS NO. 2517682-14-1] (R)-NVS-ZP7-4
PRODUCTS SPECIFICATIONS [2517682-14-1]
DESCRIPTION [2517682-14-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 501.62 |
| Molecular Formula | C28H28FN5OS |
| SMILES | O=C(NC12CCN(C[C@H](NC3=NC4=CC=C(F)C=C4S3)CC5=CC=CC=C5)CC2)NC6=C1C=CC=C6 |
1 Publications Citing Use of MCE
Summary
(R)-NVS-ZP7-4 is the R-isomer of NVS-ZP7-4. NVS-ZP7-4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL ( 199.35 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.9935 mL | 9.9677 mL | 19.9354 mL |
| 5 mM | 0.3987 mL | 1.9935 mL | 3.9871 mL |
| 10 mM | 0.1994 mL | 0.9968 mL | 1.9935 mL |
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Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: 2.5 mg/mL (4.98 mM); Clear solution; Need ultrasonic
