[CAS NO. 2230810-28-1] Tuberculosis inhibitor 1

Name: Tuberculosis inhibitor 1
Brand: Arctom Scientific
SKU: HY-119938

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PRODUCTS SPECIFICATIONS [2230810-28-1]

Fulfillment

Catalog

HY-119938

Brand

MCE

CAS

2230810-28-1

DESCRIPTION [2230810-28-1]

Overview

MDL	-
Molecular Weight	563.69
Molecular Formula	C34H37N5O3
SMILES	O=C(CC1=C(C)NC2=C1C=C(OC)C=C2)N(CCN(CC3CCOC3)C4)C4C5=NC=C(N5)C6=CC(C=CC=C7)=C7C=C6

For research use only. We do not sell to patients.

Summary

Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC ₅₀ of 5 nM ^[1] .

IC50 & Target

EC50: 5 nM (Trypanosoma brucei) ^[1]

In Vitro

Tuberculosis inhibitor 1 is selective over other parasites, such as Trypanosoma cruzi and Plasmodium falciparum ( T. cruzi EC ₅₀ 8120 nM, P. falciparum EC ₅₀ 3624 nM) ^[1] .

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Ferrigno F, et al. Discovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitorsof Trypanosoma brucei growth in vitro. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3689-3692.