[CAS NO. 50935-71-2] Kirromycin
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PRODUCTS SPECIFICATIONS [50935-71-2]
Catalog
HY-122386
Brand
MCE
CAS
50935-71-2
DESCRIPTION [50935-71-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 796.94 |
| Molecular Formula | C43H60N2O12 |
| SMILES | O=C(NC/C=C/C=C(C)/[C@@H](OC)[C@H]([C@]([C@H]([C@H]1O)O)([H])O[C@@H]1/C=C/C=C/C=C(C)/C(C(C2=O)=C(C=CN2)O)=O)C)[C@H]([C@@](O[C@H](C(C)3C)/C=C/C=C\C)([C@@H]([C@@H]3O)O)O)CC |
For research use only. We do not sell to patients.
Summary
Kirromycin (Mocimycin) is an antibiotic produced by Streptomyces collinus Tu 365. Kirromycin is a bacterial protein synthesis inhibitor that immobilizes elongation factor Tu (EF-Tu) on the elongating ribosome [1] [2] .
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
References
- [1] H Wolf, et al. Kirromycin, an inhibitor of protein biosynthesis that acts on elongation factor Tu. Proc Natl Acad Sci U S A. 1974 Dec;71(12):4910-4.
- [2] Lian N Olsthoorn-Tieleman, et al. Elongation factor Tu3 (EF-Tu3) from the kirromycin producer Streptomyces ramocissimus Is resistant to three classes of EF-Tu-specific inhibitors. J Bacteriol. 2007 May;189(9):3581-90.
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