[CAS NO. 2550398-71-3] Lenalidomide-C5-NH2TFA
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PRODUCTS SPECIFICATIONS [2550398-71-3]
Distributor
Catalog
HY-122725A
Brand
MCE
CAS
2550398-71-3
DESCRIPTION [2550398-71-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 443.42 |
| Molecular Formula | C20H24F3N3O5 |
| SMILES | O=C(C(N(CC1=C2C=CC=C1CCCCCN)C2=O)CC3)NC3=O.OC(C(F)(F)F)=O |
For research use only. We do not sell to patients.
Summary
IC50 & Target
|
Cereblon |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
References
- [1] Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018;61(2):462-481.
- [2] Li Y, Yang J, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019;62(2):448-466.
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