[CAS NO. 2920469-94-7] (2S,3R)-Voruciclibhydrochloride

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PRODUCTS SPECIFICATIONS [2920469-94-7]

Catalog

HY-12422B

Brand

MCE

CAS

2920469-94-7

MDL	-
Molecular Weight	506.30
Molecular Formula	C22H20Cl2F3NO5
SMILES	Cl[H].ClC1=CC(C(F)(F)F)=CC=C1C(OC2=C(C(O)=CC(O)=C23)[C@H]([C@H]4CO)CCN4C)=CC3=O

For research use only. We do not sell to patients.

(2S,3R)-Voruciclib hydrochloride is the enantiomer of Voruciclib hydrochloride. (2S,3R)-Voruciclib is an orally active CDK inhibitor.

Solid

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

In Vitro:

DMSO : ≥ 250 mg/mL ( 493.78 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.08 mg/mL (4.11 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (4.11 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.08 mg/mL (4.11 mM); Clear solution

* All of the co-solvents are available by MCE.