[CAS NO. 2361144-71-8] TAB29

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PRODUCTS SPECIFICATIONS [2361144-71-8]

Catalog

HY-128592

Brand

MCE

CAS

2361144-71-8

DESCRIPTION [2361144-71-8]

Overview

MDL	-
Molecular Weight	406.47
Molecular Formula	C28H22O3
SMILES	C1(OCC2=CC=CC=C2)=CC(OCC3=CC=CC=C3)=C4C(OC=C4C5=CC=CC=C5)=C1

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Summary

TAB29 is a potent inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) with an IC ₅₀ of 874 nM, possesses therapeutic potential for human cancers ^[1] .

IC50 & Target

IC50：874 nM (Pin1) ^[1]

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Fan X, et al. Discovery of 4,6-bis(benzyloxy)-3-phenylbenzofuran as a novel Pin1 inhibitor to suppress hepatocellular carcinoma via upregulating microRNA biogenesis. Bioorg Med Chem. 2019 Jun 1;27(11):2235-2244.