Mal-NH-PEG8-Boc
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 648.74 |
| Molecular Formula | C30H52N2O13 |
| SMILES | O=C1C=CC(N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O)=O)=O |
Summary
IC50 & Target
|
PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Oil
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 500 mg/mL ( 770.72 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.5414 mL | 7.7072 mL | 15.4145 mL |
| 5 mM | 0.3083 mL | 1.5414 mL | 3.0829 mL |
| 10 mM | 0.1541 mL | 0.7707 mL | 1.5414 mL |