[CAS NO. ]  XL388-C2-amide-PEG9-NH2hydrochloride

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PRODUCTS SPECIFICATIONS

Store
Catalog
HY-139085A
Brand
MCE
CAS
-

DESCRIPTION

Overview

MDL-
Molecular Weight944.50
Molecular FormulaC43H63ClFN5O13S
SMILESO=C(NCCS(=O)(C1=CC=C(C(N2CCOC3=CC=C(C4=CC=C(N)N=C4)C=C3C2)=O)C(C)=C1F)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN.[H]Cl

For research use only. We do not sell to patients.

Summary

XL388-C2-amide-PEG9-NH2 hydrochloride is an intermediate used in the synthesis of C26-linked Rapamycin analog [1] .


Appearance

Oil


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)


Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL ( 264.69 mM ; Need ultrasonic)

H 2 O : 100 mg/mL ( 105.88 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0588 mL 5.2938 mL 10.5876 mL
5 mM 0.2118 mL 1.0588 mL 2.1175 mL
10 mM 0.1059 mL 0.5294 mL 1.0588 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: PBS

    Solubility: 100 mg/mL (105.88 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 4.17 mg/mL (4.42 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 4.17 mg/mL (4.42 mM); Clear solution

  • 4.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 4.17 mg/mL (4.42 mM); Clear solution

* All of the co-solvents are available by MCE.