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[CAS NO. 686301-48-4] NB001
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-14425 |
| Brand: | MCE |
| CAS: | 686301-48-4 |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 264.33 |
| Molecular Formula | C12H20N6O |
| SMILES | OCCCCCNCCN1C=NC2=C(N)N=CN=C12 |
Summary
NB001 (HTS 09836) is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity [1] .
IC50 & Target
AC1 [1]
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date | Phase |
|---|---|---|---|---|
| NCT00453401 | NanoBio Corporation |
Herpes Labialis
|
February 2007 | Phase 2 |
| NCT05290493 | Nobias Therapeutics, Inc. |
22q11 Deletion Syndrome
|
February 10, 2022 | Phase 2 |
| NCT01324466 | NanoBio Corporation |
Recurrent Herpes Labialis
|
April 2011 | Phase 3 |
| NCT01695187 | NanoBio Corporation |
Herpes Labialis
|
October 2012 | Phase 3 |
| NCT01321359 | NanoBio Corporation |
Recurrent Herpes Simplex Labialis
|
April 2011 | Phase 3 |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 50 mg/mL ( 189.16 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.7831 mL | 18.9157 mL | 37.8315 mL |
| 5 mM | 0.7566 mL | 3.7832 mL | 7.5663 mL |
| 10 mM | 0.3783 mL | 1.8916 mL | 3.7832 mL |
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