[CAS NO. 2871872-79-4]  DS96432529

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PRODUCTS SPECIFICATIONS [2871872-79-4]

Catalog
HY-145121
Brand
MCE
CAS
2871872-79-4

DESCRIPTION [2871872-79-4]

Overview

MDL-
Molecular Weight378.49
Molecular FormulaC18H26N4O3S
SMILESO=C(C1=C(N)C2=C(N3C[C@@H](COCCOCC)CCC3)C=CN=C2S1)N

For research use only. We do not sell to patients.

Summary

DS96432529 is a potent and orally active bone anabolic agent through CDK8 inhibition.


IC50 & Target

CDK8


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture and light

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 264.21 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6421 mL 13.2104 mL 26.4208 mL
5 mM 0.5284 mL 2.6421 mL 5.2842 mL
10 mM 0.2642 mL 1.3210 mL 2.6421 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.61 mM); Clear solution

* All of the co-solvents are available by MCE.