| MDL | - |
|---|---|
| Molecular Weight | 378.49 |
| Molecular Formula | C18H26N4O3S |
| SMILES | O=C(C1=C(N)C2=C(N3C[C@@H](COCCOCC)CCC3)C=CN=C2S1)N |
DS96432529 is a potent and orally active bone anabolic agent through CDK8 inhibition.
|
CDK8 |
Solid
Room temperature in continental US; may vary elsewhere.
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
DMSO : 100 mg/mL ( 264.21 mM ; Need ultrasonic)
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.6421 mL | 13.2104 mL | 26.4208 mL |
| 5 mM | 0.5284 mL | 2.6421 mL | 5.2842 mL |
| 10 mM | 0.2642 mL | 1.3210 mL | 2.6421 mL |
Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (6.61 mM); Clear solution