[CAS NO. ]  AminobenzenesulfonicauristatinETFA

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PRODUCTS SPECIFICATIONS

Store
Catalog
HY-145989A
Brand
MCE
CAS
-

DESCRIPTION

Overview

MDL-
Molecular Weight867.03
Molecular FormulaC39H65F3N6O10S
SMILESC[C@@H](C(N[S](=O)(C(C=C1)=CC=C1N)=O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@@H](N(C)C)C(C)C)=O)=O)=O)OC.O=C(O)C(F)(F)F

For research use only. We do not sell to patients.

Summary

Aminobenzenesulfonic auristatin E TFA is a drug-linker conjugate for ADC . Aminobenzenesulfonic auristatin E TFA has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic [1] .


IC50 & Target

Auristatin


In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)