Wnt/β-catenin agonist 3 hydrochloride
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 367.23 |
| Molecular Formula | C16H16Cl2N4O2 |
| SMILES | O=C(C1=NOC(C2=CC=C(Cl)C=C2)=C1)NCCCN3C=CN=C3.[H]Cl |
Summary
Wnt/β-catenin agonist 3 hydrochloride is a Wnt/β-catenin signalling pathway agonist. Wnt/β-catenin agonist 3 (compound 98) can be used for the research of osteoporosis [1] .
In Vitro
Wnt/β-catenin agonist 3 hydrochloride (compound 98; 24 h; HEK293 and SW480 cells) has 54% cell activity at 120 μM concentration compared with the positive control group LiCl (20mM)
[1]
.
Wnt/β-catenin agonist 3 hydrochloride (30 and 60 μM; 24 h; HEK293 cells) is an activator for β-Catenin and deposits β-catenin
[1]
.
Wnt/β-catenin agonist 3 hydrochloride (11 μM; 4 d) induces differentiation of ST2 cell line into osteoblasts and calcium deposition
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
