MDL | - |
---|---|
Molecular Weight | 269.23 |
Molecular Formula | C10H12FN5O3 |
SMILES | O=C(N=C(N)N1)C2=C1N([C@@H]3O[C@H](CO)[C@@H](F)C3)C=N2 |
HBV [1]
Lagociclovir (FLG) (6 days) shows inhibitory activity with IC
50
s of 8 ± 3.8, 9 ± 2.5, 13 ± 3.4 and 15 ± 6.8 μM against 3TC-R
HBV
, wt
HBV
, PMEA-R
HBV
and 3TC+PMEA-R
HBV
, respectively in transiently transfected Huh7 cells
[1]
.
Lagociclovir (0-100 μM; 6 days) inhibits the replication of wild-type and drug-resistant mutants of
HBV
in transiently transfected Huh7 cells
[1]
.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Room temperature in continental US; may vary elsewhere.
Please store the product under the recommended conditions in the Certificate of Analysis.