[CAS NO. 2725074-96-2] Chitin synthase inhibitor 9
PRODUCTS SPECIFICATIONS [2725074-96-2]
DESCRIPTION [2725074-96-2]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 451.47 |
| Molecular Formula | C24H25N3O6 |
| SMILES | O=C(NC1=CC=CC=C1OC)/C=C/C(N2CCC3(CC2)C4=CC(OC)=CC=C4NC(O3)=O)=O |
Summary
IC50 & Target
Chitin synthase [1]
In Vitro
Chitin synthase inhibitor 9 (compound 9j, 300 μg/mL) inhibits chitin synthase (CHS) by 60%
[1]
.
Chitin synthase inhibitor 9 (0.0625-0.25 μM, 24 h) shows antifungal activities
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay [1]
| Cell Line: | C. albicans , A. flavus , A. fumigatus , C. neoformans |
| Concentration: | 1-512 μg/mL |
| Incubation Time: | 1-512 μg/mL |
| Result: | Inhibited four fungi with IC 50 value of 64, 128, 128, 256 μg/mL respectively. |
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
