[CAS NO. 2725074-94-0] Antifungal agent 39
PRODUCTS SPECIFICATIONS [2725074-94-0]
DESCRIPTION [2725074-94-0]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 455.89 |
| Molecular Formula | C23H22ClN3O5 |
| SMILES | O=C(NC1=CC=CC=C1Cl)/C=C/C(N2CCC3(CC2)C4=CC(OC)=CC=C4NC(O3)=O)=O |
Summary
Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent [1] .
IC50 & Target
Fungal [1]
In Vitro
Antifungal agent 39 (Compound 9h) (0-512 μg/mL; 24 h) shows excellent antifungal activity against C. albicans and displays good antifungal activity against A. fumigatus and C. neoformans [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Viability Assay [1]
| Cell Line: | C. albicans (ATCC 76615), A. flavus (ATCC 16870), A. fumigatus (GIMCC 3.19) and C. neoformans (ATCC 208821) |
| Concentration: | 0-512 μg/mL |
| Incubation Time: | 24 h |
| Result: | Showed inhibition with MICs of 16 ± 0, 64 ± 0, 32 ± 0 and 32 ± 0 μg/mL against C. albicans (ATCC 76615), A. flavus (ATCC 16870), A. fumigatus (GIMCC 3.19) and C. neoformans (ATCC 208821), respectively. |
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.