[CAS NO. ]  Antifungal agent 43

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PRODUCTS SPECIFICATIONS

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Catalog
HY-151442
Brand
MCE
CAS
-

DESCRIPTION

Overview

MDL-
Molecular Weight528.41
Molecular FormulaC24H26N4Se2
SMILESCC1=CC=C(C([Se][Se]C(C2=CC=C(C)C=C2)CN3C=CN=C3)CN4C=CN=C4)C=C1

For research use only. We do not sell to patients.

Summary

Antifungal agent 43 (compound B05) is an antifungal agent. Antifungal agents 43 has antifungal activity by inhibiting biofilm formation. Antifungal agent 43 has low toxicity in human cancer cell lines [1] .


In Vitro

Antifungal agent 43 (compound B05; 0.25-128 μg/mL) has antifungal activity against fungi strains with MIC values of 1, 1, 4, 4, 8, and 8 μg/mL for C.alb(sc5314), C.zey, C.alb, C.par, C.gla, and C.kru, respectively [1] .
Antifungal agent 43 (0.25-128 μg/mL) has antifungal activity against azole-resistant strains with MIC values of 2, 4, 4, 4, and 32 μg/mL for strain CaR, strain 632, strain 901, strain 904, and strain 17#, respectively [1] .
Antifungal agent 43 (0-10 μM) has low toxicity in human cancer cell lines with IC 50 values of 5.04, 7.43 and 14.74 for MDA-MB-231, PC-3, and HL-60 cells, respectively [1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


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Please store the product under the recommended conditions in the Certificate of Analysis.