ZIKV-IN-5
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 583.83 |
| Molecular Formula | C36H45NO4Si |
| SMILES | O=C1OCC=C1/C=C/[C@@H]2C(CC[C@]3([H])[C@](C)(CO[Si](C4=CC=CC=C4)(C(C)(C)C)C5=CC=CC=C5)/C(CC[C@@]23C)=N/O)=C |
Summary
ZIKV-IN-5 (compound 5c) is a low-cytotoxicity and acid-stable anti- ZIKV agent ( EC 50 =0.71 μM). ZIKV-IN-5 effectively inhibits the activity of ZIKV NS5 MTase [1] .
IC50 & Target
EC50:0.71 μM (ZIKV) [1] .
In Vitro
ZIKV-IN-5 (0-200 μM; 96 h) shows low cytotoxicity [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Cell Cytotoxicity Assay [1]
| Cell Line: | Vero cells |
| Concentration: | 0-200 μM |
| Incubation Time: | 96 h |
| Result: | Exhibited low cytotoxicities with a CC 50 value of more than 200 μM |
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.