[CAS NO. ] SARS-CoV-2/MERS Mpro-IN-2

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PRODUCTS SPECIFICATIONS

Catalog

HY-151991

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	589.47
Molecular Formula	C28H30Cl2N4O6
SMILES	O=C([C@H]1N(C(COC2=CC=C(Cl)C=C2Cl)=O)CCC1)N[C@H](C(C(NCC3=CC=CC=C3)=O)=O)C[C@H]4C(NCC4)=O

For research use only. We do not sell to patients.

Summary

SARS-CoV-2/MERS Mpro-IN-2 (compound 9d) is a potent SARS-CoV-2 and MERS main protease inhibitor with IC ₅₀ values of 0.21, 0.07 µM, respectively ^[1] .

IC50 & Target

IC ₅₀ : 0.21 µM (SARS-CoV-2); 0.07 µM (MERS) ^[1]

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

References

[1] Pelliccia S, et al. Easy access to α-ketoamides as SARS-CoV-2 and MERS Mpro inhibitors via the PADAM oxidation route. Eur J Med Chem. 2022 Dec 15;244:114853.