MDL | - |
---|---|
Molecular Weight | 441.52 |
Molecular Formula | C24H31N3O5 |
SMILES | O=C(OCC1=CC=CC=C1)N[C@@H](CC2CC2)C(N[C@H](/C=C/C(C)=O)C[C@H]3C(NCC3)=O)=O |
SPR39 is a potent SARS-CoV-2 main protease inhibitor with K i values of 0.252, 3.38, 7.88 µM for SARS-CoV-2 M pro , hCatL, hCatB, respectively. SPR39 shows antiviral and cytotoxicity [1] .
K i : 0.252 µM (SARS-CoV-2 M pro ); 3.38 µM (hCatL); 7.88 µM (hCatB) [1]
SPR39 (0-100 µM; 1 h) shows antiviral and cytotoxicity with EC 50 of 1.5 µM for SARS-CoV-2 infected Huh-7-ACE2 cells and CC 50 of 100 µM for Huh-7-ACE2 cells [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Room temperature in continental US; may vary elsewhere.
Please store the product under the recommended conditions in the Certificate of Analysis.