SPR41
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 483.60 |
| Molecular Formula | C27H37N3O5 |
| SMILES | O=C(OCC1=CC=CC=C1)N[C@@H](CC2CCCCC2)C(N[C@H](/C=C/C(C)=O)C[C@H]3C(NCC3)=O)=O |
Summary
SPR41 is a potent SARS-CoV-2 main protease inhibitor with K i values of 0.184, 0.252, 14.4 µM for SARS-CoV-2 M pro , hCatL, hCatB, respectively. SPR41 shows antiviral and cytotoxicity [1] .
IC50 & Target
K i : 0.184 µM (SARS-CoV-2 M pro ); 0.252 µM (hCatL); 14.4 µM (hCatB) [1]
In Vitro
SPR41 (0-100 µM; 1 h) shows antiviral and cytotoxicity with EC 50 of 1.8 µM for SARS-CoV-2 infected Huh-7-ACE2 cells and CC 50 of 14.5 µM for Huh-7-ACE2 cells [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.