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Catalog: | HY-152537 |
Brand: | MCE |
CAS: | - |
MDL | - |
---|---|
Molecular Weight | 417.55 |
Molecular Formula | C24H31N7 |
SMILES | CC1=CC(NCCCN2CCCC2)=NC(NC3=NC4=C5CCCC5=CC=C4C(C)=N3)=N1 |
Antitumor agent-84 (compound 21a) is a G-quadruplex (G4)-ligand with the ability to stabilize different G4-DNA structures. Antitumor agent-84 has highly effective anti-tumor properties [1] .
Antitumor agent-84 stabilizes the c-MYC Pu24T, c-MYC Pu22, CKit1, CKit2, KRAS and G4 DNA structures
[1]
.
Antitumor agent-84 (1-10000 nM) inhibits tumor organoids and cancer activated fibroblast (CAF) cells with IC
50
values of 161 and 2515 nM, respectively
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Room temperature in continental US; may vary elsewhere.
Please store the product under the recommended conditions in the Certificate of Analysis.
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