[CAS NO. 78887-48-6] Cholesterol- 13 C 2
PRODUCTS SPECIFICATIONS [78887-48-6]
DESCRIPTION [78887-48-6]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 388.64 |
| Molecular Formula | C2513C2H46O |
| SMILES | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C([13CH2][13C@H](CC4)O)=CC3)C |
Summary
Cholesterol- 13 C 2 is the 13 C labeled Cholesterol . Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins [1] [2] . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist [3] .
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs [1] .
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
Ethanol : 5.56 mg/mL ( 14.31 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.5731 mL | 12.8654 mL | 25.7308 mL |
| 5 mM | 0.5146 mL | 2.5731 mL | 5.1462 mL |
| 10 mM | 0.2573 mL | 1.2865 mL | 2.5731 mL |
