[CAS NO. 105990-27-0]  (S)-Higenamine hydrobromide

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PRODUCTS SPECIFICATIONS [105990-27-0]

Distributor
Catalog
HY-N2037C
Brand
MCE
CAS
105990-27-0

DESCRIPTION [105990-27-0]

Overview

MDL-
Molecular Weight352.22
Molecular FormulaC16H18BrNO3
SMILESOC1=CC2=C([C@H](CC3=CC=C(O)C=C3)NCC2)C=C1O.[H]Br

For research use only. We do not sell to patients.

Summary

(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) [1] .


In Vitro

The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine [1] .

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)