[CAS NO. 118506-26-6] Myelin Basic Protein(87-99)

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PRODUCTS SPECIFICATIONS [118506-26-6]

Catalog

HY-P1052

Brand

MCE

CAS

118506-26-6

DESCRIPTION [118506-26-6]

Overview

MDL	-
Molecular Weight	1555.82
Molecular Formula	C74H114N20O17
SMILES	F[VH](F)([K])([V](P([3H])[R][P])[3H])=NI

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Summary

Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS) ^[1] ^[2] .

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References

[1] R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12.
[2] George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J M