[CAS NO. ] D[LEU4,LYS8]-VP TFA

Name: D[LEU4,LYS8]-VP TFA
Brand: Arctom Scientific
SKU: HY-P1163A

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PRODUCTS SPECIFICATIONS

Distributor

Catalog

HY-P1163A

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	1140.25
Molecular Formula	C49H68F3N11O13S2
SMILES	-

For research use only. We do not sell to patients.

Summary

D[LEU4,LYS8]-VP TFA is a selective agonist of vasopressin V _1b receptor , with the K _i s of 0.16 nM, 0.52 nM, and 0.1.38 nM for rat, human and mouse V _1b receptor, respectively. D[LEU4,LYS8]-VP TFA has weak antidiuretic, vasopressor, and in vitro oxytocic activities ^[1] ^[2] .

IC50 & Target

vasopressin V _1b receptor ^[1]

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H ₂ O : 100 mg/mL ( 87.70 mM ; Need ultrasonic)

DMSO : ≥ 100 mg/mL ( 87.70 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.8770 mL	4.3850 mL	8.7700 mL
5 mM	0.1754 mL	0.8770 mL	1.7540 mL
10 mM	0.0877 mL	0.4385 mL	0.8770 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (2.19 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (2.19 mM); Clear solution

* All of the co-solvents are available by MCE.