UFP-101 TFA
PRODUCTS SPECIFICATIONS
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | 2022.19 |
| Molecular Formula | C84H139F3N32O23 |
| SMILES | - |
Summary
In Vivo
UFP-101 TFA elicits a pronounced acute and dosedependent antidepressant-like effect in mice submitted to the forced swimming test (FST) [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Sealed storage, away from moisture and light
| Powder | -80°C | 2 years |
|---|---|---|
| -20°C | 1 year |
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
H 2 O : 130 mg/mL ( 64.29 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 0.4945 mL | 2.4726 mL | 4.9451 mL |
| 5 mM | 0.0989 mL | 0.4945 mL | 0.9890 mL |
| 10 mM | 0.0495 mL | 0.2473 mL | 0.4945 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (49.45 mM); Clear solution; Need ultrasonic
References
- [1] Calo G, et al. [Nphe ,Arg ,Lys ]nociceptin-NH , a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor. Br J Pharmacol. 2002;136(2):303-311.
- [2] Gavioli EC, et al. Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test. Eur J Neurosci. 2003;17(9):1987-1990.
