[CAS NO. ]  Difopein TFA

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PRODUCTS SPECIFICATIONS

Catalog
HY-P1380A
Brand
MCE
CAS
-

DESCRIPTION

Overview

MDL-
Molecular Weight6501.19
Molecular FormulaC275H425N76F3O91S6
SMILES-

For research use only. We do not sell to patients.

Summary

Difopein (TFA), a specific and competitive inhibitor of 14-3-3 protein (a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction of apoptosis and enhances the ability of cisplatin to kill cells [1] .


IC50 & Target

14-3-3 protein [1]


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)