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[CAS NO. ] Urotensin II, mouse TFA
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-P1483A |
| Brand: | MCE |
| CAS: | - |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 1747.88 |
| Molecular Formula | C78H101N18F3O21S2 |
| SMILES | - |
Summary
Urotensin II, mouse TFA is an endogenous ligand for the orphan G-protein-coupled receptor GPR14 or SENR. Urotensin II, mouse TFA is a potent vasoconstrictor. Urotensin II, mouse TFA plays a physiological role in the central nervous system [1] .
IC50 & Target
GPR14 [1]
In Vivo
Urotensin II is a somatostatin-like cyclic peptide which functions as an arterial vasocontrictor, vasodilator, and bronchoconstriction mediator
[1]
.
Urotensin II (0.1 nmol, 0.3 nmol, and 3 nmol; intracerebroventricular administration) induces anxiogenic-like behaviors in the elevated plus maze test and the hole-board test in mice in a dose-dependent manner
[1]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
| Animal Model: | Male C57BL/6N mice (8 weeks old) [1] |
| Dosage: | 0.1 nmol, 0.3 nmol, and 3 nmol |
| Administration: | Intracerebroventricular (i.c.v.) administration |
| Result: | Decreased the amount of head dipping without significant alteration of the motor activity. |
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Sealed storage, away from moisture
| Powder | -80°C | 2 years |
|---|---|---|
| -20°C | 1 year |
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H 2 O : 50 mg/mL ( 28.61 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 0.5721 mL | 2.8606 mL | 5.7212 mL |
| 5 mM | 0.1144 mL | 0.5721 mL | 1.1442 mL |
| 10 mM | 0.0572 mL | 0.2861 mL | 0.5721 mL |
-
1.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (57.21 mM); Clear solution; Need ultrasonic
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