[CAS NO. ] Caerulein, desulfated TFA

Name: Caerulein, desulfated TFA
Brand: Arctom Scientific
SKU: HY-P1800A

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PRODUCTS SPECIFICATIONS

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Catalog

HY-P1800A

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	1386.36
Molecular Formula	C60H74F3N13O20S
SMILES	-

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6622-6629.

Summary

Caerulein, desulfated TFA is the desulfurated form of Caerulein. Caerulein is a decapeptide having the same five carboxyl-terminal amino acids as gastrin and cholecystokinin (CCK) ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 72.13 mM ; Need ultrasonic)

H ₂ O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.7213 mL	3.6066 mL	7.2131 mL
5 mM	0.1443 mL	0.7213 mL	1.4426 mL
10 mM	0.0721 mL	0.3607 mL	0.7213 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (1.80 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: 2.5 mg/mL (1.80 mM); Suspended solution; Need ultrasonic
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (1.80 mM); Clear solution

* All of the co-solvents are available by MCE.

References

[1] Johnson LR, et al. Effect of sulfation on the gastrointestinal actions of caerulein. Gastroenterology. 1970 Feb;58(2):208-16.