MDL | - |
---|---|
Molecular Weight | 1605.76 |
Molecular Formula | C66H112N18O26S |
SMILES | - |
The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Solid
Room temperature in continental US; may vary elsewhere.
Sealed storage, away from moisture
Powder | -80°C | 2 years |
---|---|---|
-20°C | 1 year |
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
H 2 O : 100 mg/mL ( 62.28 mM ; Need ultrasonic)
Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
---|
1 mM | 0.6228 mL | 3.1138 mL | 6.2276 mL |
5 mM | 0.1246 mL | 0.6228 mL | 1.2455 mL |
10 mM | 0.0623 mL | 0.3114 mL | 0.6228 mL |
Add each solvent one by one: PBS
Solubility: 100 mg/mL (62.28 mM); Clear solution; Need ultrasonic