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[CAS NO. ] hFSH-β-(33-53) (TFA)
| Ships within | Stock | Price | Qty | Total |
Please click "REQUEST A QUOTE" button if there is no stock, or you need other sizes or custom synthesis.
| Catalog: | HY-P3343A |
| Brand: | MCE |
| CAS: | - |
Overview
| MDL | - |
|---|---|
| Molecular Weight | 2657.96 |
| Molecular Formula | C₁₁₇H₁₈₄F₃N₃₁O₃₄S |
| SMILES | - |
Summary
hFSH-β-(33-53) TFA, a thiol-containing peptide which corresponds to a second FSH receptor-binding domain, is a FSHR (follicle-stimulating hormone receptor) antagonist. hFSH-β-(33-53) TFA inhibits binding of FSH to receptor and is a partial agonist of estradiol synthesis in Sertoli cells [1] [2] [3] .
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Sealed storage, away from moisture
| Powder | -80°C | 2 years |
|---|---|---|
| -20°C | 1 year |
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL ( 37.62 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 0.3762 mL | 1.8811 mL | 3.7623 mL |
| 5 mM | 0.0752 mL | 0.3762 mL | 0.7525 mL |
| 10 mM | 0.0376 mL | 0.1881 mL | 0.3762 mL |
References
- [1] Grasso P, et al. A synthetic peptide corresponding to hFSH-beta-(81-95) has thioredoxin-like activity. Mol Cell Endocrinol. 1991;78(3):163-170.
- [2] Xu Y, et al. Pilot study of a novel (18)F-labeled FSHR probe for tumor imaging. Mol Imaging Biol. 2014;16(4):578-585.
- [3] Santa-Coloma TA, et al. Serine analogues of hFSH-beta-(33-53) and hFSH-beta-(81-95) inhibit hFSH binding to receptor. Biochem Biophys Res Commun. 1992;184(3):1273-1279.
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