[CAS NO. ] Z-DEVD-AMC

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PRODUCTS SPECIFICATIONS

Catalog

HY-P3363

Brand

MCE

CAS

-

DESCRIPTION

Overview

MDL	-
Molecular Weight	767.74
Molecular Formula	C36H41N5O14
SMILES	-

For research use only. We do not sell to patients.

Summary

Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates ^[1] .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light, under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility

In Vitro:

DMSO : 33.33 mg/mL ( 43.41 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3025 mL	6.5126 mL	13.0252 mL
5 mM	0.2605 mL	1.3025 mL	2.6050 mL
10 mM	0.1303 mL	0.6513 mL	1.3025 mL

* Please refer to the solubility information to select the appropriate solvent.

References

[1] Mauro C X Pinto, et al. Discovery of cytotoxic and pro-apoptotic compounds against leukemia cells: Tert-butyl-4-[(3-nitrophenoxy) methyl]-2,2-dimethyloxazolidine-3-carboxylate. Life Sci. 2011 Nov 21;89(21-22):786-94.