[CAS NO. ] Latent TGF beta 1/TGFB1 Protein, Human (C33S, HEK293, His)

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PRODUCTS SPECIFICATIONS

Catalog

HY-P70236

Brand

MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	38-55&13 kDa
Molecular Formula	-
SMILES	-

For research use only. We do not sell to patients.

Summary

Latent TGF beta 1/TGFB1 Protein is a large extracellular matrix protein and an associated ligand of fibrillinmicrofibrils. TGF beta 1/TGFB1 Protein, Human (361a.a, HEK293, His) is a recombinant Biotinylated protein (L30-S390) produced by HEK293 cells with His tag ^[1] ^[2] .

Appearance

Lyophilized powder.

Source

HEK293

Shipping

Room temperature in continental US; may vary elsewhere.

References

[1] J Taipale, et al. Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein. J Cell Biol. 1994 Jan;124(1-2):171-81.
[2] C Unsöld, et al. Latent TGF-beta binding protein LTBP-1 contains three potential extracellular matrix interacting domains. J Cell Sci. 2001 Jan;114(Pt 1):187-197.
[3] Matthias Przyklenk, et al. LTBP1 promotes fibrillin incorporation into the extracellular matrix. bioRxiv. 2022.
[4] Rui Cai, et al. LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation. J Transl Med. 2020 Mar 26;18(1):139.
[5] Xiaojun Fu, et al. LTBP1 plays a potential bridge between depressive disorder and glioblastoma. J Transl Med. 2020 Oct 15;18(1):391.