[CAS NO. ] TNFRSF1A Protein, Human (His)

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PRODUCTS SPECIFICATIONS

Catalog

HY-P70801

Brand

MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	Approximately 22.0 kDa
Molecular Formula	-
SMILES	-

For research use only. We do not sell to patients.

Summary

TNFRSF1A (TNF RI) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRSF1A is a STAT3 target gene that regulates the NF-κB pathway. TNFRSF1A activate NF-κB, mediate apoptosis, and function as a regulator of inflammation. TNFRSF1A Protein, Human (His) is expressed by E. coli and has a transmembrane region (I22-T211) with a 6*His tag at the N-terminus ^[1] .

Appearance

Lyophilized powder.

Source

E. coli

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Room temperature in continental US;may vary elsewhere.

References

[1] Wajant H, et, al. Tumor necrosis factor signaling. Cell Death Differ. 2003 Jan;10(1):45-65.
[2] Fu Q, et, al. miR-29a up-regulation in AR42J cells contributes to apoptosis via targeting TNFRSF1A gene. World J Gastroenterol. 2016 May 28;22(20):4881-90.
[3] Zhou S, et, al. Bioinformatics Analysis Identifies TNFRSF1A as a Biomarker of Liver Injury in Sepsis TNFRSF1A is a Biomarker for Septic Liver Injury. Genet Res (Camb). 2022 Oct 15;2022:1493744.
[4] Egusquiaguirre SP, et, al. The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells. Neoplasia. 2018 May;20(5):489-498.