[CAS NO. ] CNTF Protein, Rat

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PRODUCTS SPECIFICATIONS

Catalog

HY-P7148

Brand

MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	Approximately 22.9 kDa
Molecular Formula	-
SMILES	-

For research use only. We do not sell to patients.

Summary

CNTF is a pluripotent neurotrophic factor, belonging to the IL-6 cytokine family ^[1] . CNTF could protect retinal cone and rod photoreceptors ^[2] . CNTF has neuroprotective effects on a variety of central and also peripheral nervous system neurons ^[3] . CNTF Protein, Rat is produced by E. coli (A2-M200) with tag freeg.

Appearance

Lyophilized powder.

Source

E. coli

Shipping

Room temperature in continental US; may vary elsewhere.

References

[1] Jones SA, et al. Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer. Nat Rev Immunol. 2018 Dec;18(12):773-789.
[2] Li S, et al. Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments. J Biol Chem. 2018 Sep 28;293(39):15256-15268.
[3] Abbaszadeh HA, et al. Human ciliary neurotrophic factor-overexpressing stable bone marrow stromal cells in the treatment of a rat model of traumatic spinal cord injury. Cytotherapy. 2015 Jul;17(7):912-21.
[4] Saadat S, et al. Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture[J]. The Journal of cell biology, 1989, 108(5): 1807-1816.