[CAS NO. ] MCP-1/CCL2 Protein, Mouse (HEK293)

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PRODUCTS SPECIFICATIONS

Catalog

HY-P7235

Brand

MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	Approximately 8 kDa
Molecular Formula	-
SMILES	-

For research use only. We do not sell to patients.

Summary

MCP-1/CCL2 Protein, Mouse (HEK293) is a cytokine belonging to the CC chemokine family that interacts with the CCR2 chemokine receptor on the cell surface to mediate inflammatory immune responses, viral infections, and tumorigenesis. MCP-1/CCL2 Protein, Mouse (HEK293) is a mouse MCP-1/CCL2 (Q24-R96) expressed by HEK293 ^[1] .

Appearance

Lyophilized powder.

Source

HEK293

Shipping

Room temperature in continental US; may vary elsewhere.

References

[1] Qiongyu Hao, et al. CCL2/CCR2 signaling in cancer pathogenesis. Cell Commun Signal. 2020 May 29;18(1):82.
[2] Svetlana M Stamatovic, et al. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J Cereb Blood Flow Metab. 2005 May;25(5):593-606.
[3] Rachel N Gomes, et al. Bacterial clearance in septic mice is modulated by MCP-1/CCL2 and nitric oxide. Shock. 2013 Jan;39(1):63-9.
[4] Lijun Zhang, et al. Effect of chemokine CC ligand 2 (CCL2) on α?synuclein?induced microglia proliferation and neuronal apoptosis. Mol Med Rep. 2018 Nov;18(5):4213-4218.