IL-17C Protein, Human (HEK293, His)
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PRODUCTS SPECIFICATIONS
Catalog
HY-P72587
Brand
MCE
CAS
-
DESCRIPTION
Overview
| MDL | - |
|---|---|
| Molecular Weight | Approximately 19 kDa |
| Molecular Formula | - |
| SMILES | - |
For research use only. We do not sell to patients.
Summary
IL-17C is an early response cytokine in the defense against bacterial pathogens and upregulates the expression of a variety of antimicrobial peptides. IL-17C stimulates the release of cytokines and is implicated in autoimmune disorders and bacterial infections [1] . IL-17C Protein, Human (HEK293, His) is a recombinant human IL-17C protein with His tag at the C-terminus and is expressed in HEK293 cells. It consists of 179 amino acids (H19-V197).
Appearance
Lyophilized powder.
Source
HEK293
Shipping
Room temperature in continental US; may vary elsewhere.
References
- [1] Swedik S, et al. IL-17C in human mucosal immunity: More than just a middle child. Cytokine. 2021 Oct;146:155641.
- [2] Lauffer F, et al. IL-17C amplifies epithelial inflammation in human psoriasis and atopic eczema. J Eur Acad Dermatol Venereol. 2020 Apr;34(4):800-809.
- [3] Johnston A, et al. Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation. J Immunol. 2013 Mar 1;190(5):2252-62.
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