[CAS NO. ] NAP-2/CXCL7 Protein, Human (CHO)

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PRODUCTS SPECIFICATIONS

Catalog

HY-P7267

Brand

MCE

CAS

DESCRIPTION

Overview

MDL	-
Molecular Weight	Approximately 9 kDa
Molecular Formula	-
SMILES	-

For research use only. We do not sell to patients.

Summary

CXCL7 (also known as neutrophil activating peptide 2, NAP-2) is a platelet-derived growth factor that belongs to the ELR ⁺ CXC chemokine family, functioning as a potent chemoattractant and activator of neutrophils through binding to its receptor CXCR2 ^[1] . NAP-2/CXCL7 Protein, Human (CHO) is produced in CHO cells, and consists of 70 amino acids (A59-D128) .

Appearance

Lyophilized powder.

Source

CHO

Shipping

Room temperature in continental US; may vary elsewhere.

References

[1] Qian Guo, et al. CXCL7 promotes proliferation and invasion of cholangiocarcinoma cells. Oncol Rep. 2017 Feb;37(2):1114-1122.
[2] Oda M, et al. Thrombopoietin-induced CXC chemokines, NAP-2 and PF4, suppress polyploidization and proplatelet formation during megakaryocyte maturation. Genes Cells. 2003 Jan;8(1):9-15.
[3] Yu-Shan Wang, et al. Canine CXCL7 and its functional expression in dendritic cells undergoing maturation. Vet Immunol Immunopathol. 2010 May 15;135(1-2):128-136.
[4] Laurens Kruidenier, et al. Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells. Gastroenterology. 2006 Jan;130(1):127-36.